Sen. Chris Romer, D-Denver, is leaving the legislature.
Romer, who was elected to second term in the Senate Nov. 2, announced Tuesday that he will resign his seat so that he can seek election as Denver's mayor.
He made his announcement at a meeting of business advocates, promising to balance the city's budget.
Early speculation has Rep. Beth McCann, D-Denver, being the most likely replacement for Romer.
A district 32 vacancy committee will have to make that decision, and McCann won't be the only option the members have.
According to a report in Wednesday's Denver Post, Denver Democratic Party secretary Owen Perkins, former federal civil servant Jeff Hart, physician Irene Aguilar, and environmentalist Matt Royster may also seek the appointment.
If McCann is appointed to fill the remainder of Romer's term, which would expire in January 2015, she would also be replaced in House district 8 by a vacancy committee.